Global Lung Function Initiative Equations: The Legacy Starts

Global Lung Function Initiative equations improve interpretation of FEV1 decline among patients with cystic fibrosis.

The prognosis for individuals with cystic fibrosis has improved markedly over the last 50 years, with most countries now reporting that 50% of the population reach at least 35 years of age [1–3]. Despite this improvement, the average age at death is still in the late 20s and varies enormously between cystic fibrosis centres and countries [4]. To further improve the trajectory of lung disease, i...

Effects of adopting the new global lung function initiative 2012 reference equations on the interpretation of spirometry.

BACKGROUND The recently generated spirometry reference equations from the Global Lung Function Initiative (GLI2012) provide a long-awaited opportunity for the adoption of a globally applicable set of normal reference values. OBJECTIVE The aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012 equ...

Global polio eradication initiative: lessons learned and legacy.

The world is on the verge of achieving global polio eradication. During >25 years of operations, the Global Polio Eradication Initiative (GPEI) has mobilized and trained millions of volunteers, social mobilizers, and health workers; accessed households untouched by other health initiatives; mapped and brought health interventions to chronically neglected and underserved communities; and establi...

Global initiative for chronic obstructive lung disease.

The Global Lung Function Initiative (GLI) Network: bringing the world’s respiratory reference values together

The Global Lung Function Initiative (GLI) Network has become the largest resource for reference values for routine lung function testing ever assembled. This article addresses how the GLI Network came about, why it is important, and its current challenges and future directions. It is an extension of an article published in Breathe in 2013 [1], and summarises recent developments and the future o...